Rapamycin has gained attention for its potential health benefits, but getting a consistent prescription can often feel frustrating.
At PonteVita Rx, we simplify the process by offering one-year online prescription refills, so you never have to worry about unnecessary delays.
Step 1: Get Rapamycin online through PonteVita Rx
Before you can order your medication, you need a valid prescription. PonteVita Rx makes this part simple with telehealth appointments that are quick, affordable, and available in all 50 states.
How it works
Here’s how the process goes from start to finish:
- First, you schedule an appointment on the PonteVita Rx platform. When booking, you’ll be asked to choose the type of visit. Since you need rapamycin (also called sirolimus), you should select “Existing Refill Evaluation – Other Medication(s) Refill”. This option ensures that your provider knows you’re requesting a prescription refill outside of the most common categories. The appointment usually takes about 15 minutes and is conducted through a secure Healthie video call or phone call.

- Once you’ve booked your slot, you’ll complete a set of health forms. These forms gather your medical history and current health details, which helps the doctor assess whether you’re a safe candidate for a one-year prescription. This part usually takes 20–30 minutes, but it’s important to answer carefully.

- Next, you’ll meet with a licensed provider. During this session, they’ll ask targeted questions about your health status, previous lab results, and your history with the medication. Some state laws require a video consultation, and PonteVita Rx always complies with those rules. If you qualify, the provider issues a prescription for up to one year, which can then be sent to any pharmacy of your choice.
- Finally, after approval, you’ll gain direct access to ongoing prescription management. You’ll also have unlimited messaging with the care team throughout your service term in case you need adjustments, clarifications, or assistance with pharmacy coordination.
Eligibility
Not everyone qualifies for a one-year rapamycin refill. To be eligible: You must already be safely established and stable on the medication.
This means you’ve been taking it consistently for at least a year without major complications. PonteVita Rx does not replace your primary doctor, so you must still follow up with them for annual exams, lab work, and recommended screenings.
If you’re new to rapamycin or have never taken it before, PonteVita Rx will not initiate the prescription. However, if you already have a doctor overseeing your care and you meet the criteria, then PonteVita Rx can provide a seamless prescription renewal.
It’s also important to note that PonteVita Rx does not prescribe controlled substances, high-risk drugs that require close monitoring, or medications outside its approved conditions. But for patients using rapamycin responsibly, the service makes long-term access much easier.
Pricing
PonteVita Rx offers transparent, subscription-style pricing based on the number of medications you need refilled. Here’s the breakdown:
| Number of Medications | Cost Per Month |
| 1–2 medications | $10 |
| 3–4 medications | $15 |
| 5 medications | $20 |
Note: This covers the prescription service only. It does not include the cost of your medication itself.
Step 2: Order through Cost Plus Drugs
Once you have your prescription from PonteVita Rx, the next step is to fill it affordably. Cost Plus Drugs is one of the best options because it offers sirolimus at transparent, wholesale-based pricing.
Price
Cost Plus Drugs currently lists rapamycin (sirolimus) in two forms. Here’s a clear look at the costs:
| Medication | Form | Strength | Quantity | Price | Retail Price Elsewhere |
| Sirolimus (generic for Rapamune) | Tablet | 2mg | 30 count | $61.24 | $905.10 |
| Sirolimus Oral Solution (generic for Rapamune Oral Solution) | Oral Solution | 1mg/mL | 60mL (1 bottle) | $233.07 | $1,080.43 |
Shipping costs are added at checkout: typically $5 for standard shipping, with higher rates for expedited or refrigerated shipments.
How to order from Cost Plus Drugs
The ordering process is straightforward, but it does require a few careful steps.
- First, go to the Cost Plus Drugs website and create an account. You’ll need to provide your full name, date of birth, and email address. Make sure these match exactly with what your doctor writes on your prescription, otherwise, the system won’t link your prescription properly.
- Next, search for your medication. Type “Sirolimus” or “Rapamune” into the search bar, then select the correct form and strength (most patients use the 2mg tablets). If your doctor prescribed the oral solution instead, you can select that option.
- Then, have your doctor send the prescription electronically to Cost Plus Drugs’ pharmacy partner, HealthDyne. If your doctor isn’t familiar with this process, you can share the “Contact Your Doctor” instructions available on the Cost Plus Drugs website.
- Once your prescription is received, you’ll get an email notification. At this point, log in to your account, confirm your shipping address, and proceed to checkout. You’ll see a full breakdown of the costs, including the manufacturing price, markup, pharmacy labor, and shipping. This transparency is part of what makes Cost Plus Drugs so valuable.
- Finally, complete payment with your credit card, HSA, or FSA. Insurance is accepted only with select plans, but even without it, the prices are often significantly lower than retail. Within a few days, your medication will be delivered straight to your door.
Frequently Asked Questions
Can PonteVita Rx prescribe new rapamycin for someone who hasn’t taken it before?
No. PonteVita Rx only provides refills for patients already stable on rapamycin under supervision of their primary doctor.
Does PonteVita Rx accept insurance?
No, but you may use insurance at the pharmacy when paying for your medication if your plan covers it.
How long does it take to get my rapamycin prescription filled through PonteVita Rx?
Usually, you can complete your telehealth visit and have a prescription sent to your pharmacy the same day.
Do I need to see my primary care doctor if I use PonteVita Rx?
Yes. PonteVita Rx is not a replacement for your doctor. You must continue your annual check-ups and labs.
Can I transfer my prescription if I move states?
Yes. PonteVita Rx can send your prescription to any pharmacy in the U.S.
Author Bio: Dr. Adrian Blackwell is the founder and CEO of PonteVita Rx, a telehealth practice dedicated to making medication access simpler, more affordable, and less stressful. Licensed to practice medicine in all 50 states and DC, Dr. Blackwell is board certified in obesity medicine and emergency medicine. He combines clinical expertise with personal experience navigating the healthcare system as a patient and parent to children with chronic illnesses. His mission: ensure everyone has access to their necessary medications without unnecessary barriers.
Medical Disclaimer: All the information here, on these videos, YouTube, social media, or in any other format, is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your personal physician or other qualified health provider with any questions you may have regarding a medical condition. Never replace professional medical advice given to you personally or delay in seeking it because of something you have read or heard on this website. This information is not meant to diagnose, treat, or cure any medical condition. No patient-physician relationship is formed. If you’re my patient, please text me before you make any changes to your medication. If you believe you are having a medical emergency please call 911.