Hormone therapy is a critical part of health for many people, but refills often feel like a never-ending chore. Between repeated doctor visits, high costs, and scheduling frustrations, it’s easy to feel overwhelmed. The good news is there’s a simpler way.
By using PonteVita Rx for prescriptions and Cost Plus Drugs for affordable fulfillment, you can secure a full year of estrogen or progesterone medication without the usual barriers.
Step 1: Get your medication online through PonteVita Rx
Managing hormone therapy should never feel like a burden. PonteVita Rx was created to simplify the refill process so you can focus on living your life, not chasing prescriptions. With a quick telehealth visit, you can secure a full year of estrogen or progesterone refills, without the repeated hassle of office visits.
- You begin by booking an appointment through the PonteVita Rx platform. When scheduling, you’ll be prompted to select an appointment type. Since you are refilling estrogen or progesterone, you should choose “Existing Refill Evaluation – Other Medication(s) Refill.” This option covers prescriptions outside the more condition-specific categories such as blood pressure or asthma.
- Once you’ve selected your slot, you’ll fill out health forms detailing your history and current use of hormone therapy. These forms allow the doctor to confirm that you are safely established on your medication. After submission, you’ll meet with a licensed provider through a short video or phone consultation. Most visits last about 15 minutes.
- During the call, the doctor will confirm your health status, review your medication regimen, and ensure you qualify for a year-long prescription. If approved, PonteVita Rx sends the prescription directly to the pharmacy of your choice. You can select a local pharmacy, a mail-order pharmacy, or an affordable online partner such as Cost Plus Drugs.
- The final step is simple. Once your prescription is on file, you gain uninterrupted access for 12 months, so you won’t face the stress of monthly or quarterly visits.
Eligibility
Not everyone is eligible for a one-year prescription. PonteVita Rx follows safety-first guidelines to protect patients while still reducing barriers. To qualify:
- You must already be stable on estrogen or progesterone for at least one year.
- You must continue routine care with your primary doctor, including annual physicals, bloodwork, and recommended screenings.
- You cannot be starting hormone therapy for the very first time. Initial management still requires in-person care.
- You must not be taking controlled medications or medicines that require close monitoring alongside your hormone therapy.
- You must not be in an acute or unstable health situation that would make extended refills unsafe.
If you meet these criteria, you are an excellent candidate for PonteVita Rx’s one-year refill program.
Pricing
PonteVita Rx uses a tiered system for prescription refills. This fee covers your yearly telehealth service and unlimited support but does not include the medication cost itself.
| Number of Medications | Monthly Cost | Yearly Total |
| 1–2 Medications | $10 / month | $120 / year |
| 3–4 Medications | $15 / month | $180 / year |
| 5 Medications | $20 / month | $240 / year |
If for any reason PonteVita Rx cannot treat you, you are not charged.
Step 2: Order through Cost Plus Drugs
After securing your prescription through PonteVita Rx, the next step is filling it affordably. This is where Mark Cuban’s Cost Plus Drugs comes in. Known for transparent pricing, this service cuts out middlemen to bring you the lowest possible cost for hormone therapy.
Price
Here are the current prices for estrogen and progesterone medications at Cost Plus Drugs:
| Medication | Strength / Form | Quantity | Price |
| Progesterone (Prometrium, generic) | 100mg capsule | 30 count | $9.45 |
| Progesterone (Prometrium, generic) | 200mg capsule | 30 count | $11.86 |
| Estradiol Oral (Estrace, generic) | 0.5mg tablet | 30 count | $6.04 |
| Estradiol Oral (Estrace, generic) | 1mg or 2mg tablet | 30 count | $6.04–$7.00 (varies) |
| Estradiol Vaginal Tablet Insert (Vagifem, generic) | 10mcg | 30 count | $113.81 |
| Estradiol Vaginal Cream (Estrace, generic) | 0.01% | 1 tube (42.5g) | $13.21 |
| Estradiol Patch (Climara, generic) | 0.025–0.1mg | 4 patches (1 month) | ~$42.13 |
| Premarin (Conjugated Estrogens) | 0.9mg tablet | 30 count | $183.11 |
| Premarin Vaginal Cream | 0.625mg/gm | 30g tube | $432.11 |
| Prempro (Estrogens/Medroxyprogesterone) | 0.3–1.5mg to 0.625–5mg | 28 tablets | $212.89–$224.26 |
| Duavee (Estrogens/Bazedoxifene) | 0.45–20mg | 30 tablets | $184.62 |
Shipping is usually $5 for standard delivery.
How to order from Cost Plus Drugs
Ordering is straightforward but does require a valid prescription. Here’s how the process works:
- Search for your medication – Go to CostPlusDrugs.com and use the search bar to find estrogen or progesterone products. You can browse alphabetically or by condition if needed.
- Create an account – You’ll be prompted to sign up with your email and personal details. Only adults 18 and older can create an account.
- Have your doctor send the prescription – PonteVita Rx can directly send your prescription electronically to Cost Plus Drugs’ pharmacy partner. Make sure your email address matches between your account and prescription.
- Wait for confirmation – Once the pharmacy receives your prescription, you’ll get an email notification that your medication is ready to purchase.
- Checkout and pay – Review the medication details, confirm shipping address, and pay with a credit card, HSA/FSA card, or insurance if supported.
- Receive home delivery – Medications are shipped directly to your door. Standard delivery takes only a few days.
Frequently asked questions
Can PonteVita Rx send my prescription directly to Cost Plus Drugs?
Yes. PonteVita Rx can electronically send prescriptions to any U.S. pharmacy, including Cost Plus Drugs.
Does PonteVita Rx accept insurance for visits?
No. You pay out-of-pocket for the yearly service. However, you can use insurance at your pharmacy if accepted.
Do I need insurance to use Cost Plus Drugs?
No. Their prices are already set at low transparent cash rates. Insurance is optional with select plans.
Can I switch pharmacies later if I start with Cost Plus Drugs?
Yes. PonteVita Rx can transfer your prescription to another pharmacy at any time.
Are hormone patches available through Cost Plus Drugs?
Yes. Estradiol patches are available in multiple strengths at around $42.13 for a month’s supply.
What happens if my prescription has no refills left?
You’ll need to return to PonteVita Rx to renew your prescription before Cost Plus Drugs can dispense more medication.
Author Bio: Dr. Adrian Blackwell is the founder and CEO of PonteVita Rx, a telehealth practice dedicated to making medication access simpler, more affordable, and less stressful. Licensed to practice medicine in all 50 states and DC, Dr. Blackwell is board certified in obesity medicine and emergency medicine. He combines clinical expertise with personal experience navigating the healthcare system as a patient and parent to children with chronic illnesses. His mission: ensure everyone has access to their necessary medications without unnecessary barriers.
Medical Disclaimer: All the information here, on these videos, YouTube, social media, or in any other format, is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your personal physician or other qualified health provider with any questions you may have regarding a medical condition. Never replace professional medical advice given to you personally or delay in seeking it because of something you have read or heard on this website. This information is not meant to diagnose, treat, or cure any medical condition. No patient-physician relationship is formed. If you’re my patient, please text me before you make any changes to your medication. If you believe you are having a medical emergency please call 911.